1000th patient enrolled at UHN

November 2022
July 2022


1st patient recruited in Nova Scotia

1st patient with Hereditary Leiomyomatosis and Renal Cell Cancer (HLRCC) recruited into CHARM

May 6, 2022
March 2022


1st patient recruited in Newfoundland and Labrador

1st Birt-Hogg-Dubé Syndrome patient enrolled into CHARM

November 16, 2021
August 30, 2021

1st Multiple Endocrine Neoplasia patient enrolled into CHARM

1000th patient recruited into CHARM

August 2021
July 28, 2021

1st Hereditary Paraganglioma-Pheochromocytoma Syndrome patient enrolled into CHARM

1st Von Hippel-Lindau disease patient recruited into CHARM

July 12, 2021
May 2021

1st patient recruited in Quebec

100th patient recruited at Mount Sinai Hospital

March 18, 2021
December 2020

1st patient recruited at BC Cancer 

200th Neurofibromatosis type 1 patient recruited into CHARM

November 11, 2020
March 9, 2020

1st child with Neurofibromatosis type 1 recruited at SickKids

75th Li-Fraumeni syndrome patient recruited into CHARM

February 3, 2020
November 27, 2019

500th patient recruited into CHARM

September 25, 2019

1st patient recruited at Mount Sinai Hospital

Recruitment of individuals with hereditary cancer syndromes began at Mount Sinai in September 2019, following the 8th annual Lynch Syndrome Education Night.

Qualitative findings from CHARM presented at 2019 ARCC

Leslie Oldfield, Project Manager at the Pugh Lab, presented qualitative findings in support of Aim 3 of the CHARM study (to optimize integration of ctDNA into clinical practice). These findings were presented at the 8th annual Canadian Centre for Applied Research in Cancer Control (ARCC) Conference in Halifax, Nova Scotia.

May 2019
March 2019

Children’s Tumor Foundation Clinical Research Award granted

The Children’s Tumor Foundation’s mission is to drive research, expand knowledge, and advance care for the NF community. Their Clinical Research Award was granted to CHARM in order to develop cell-free DNA detection technologies in application to NF1. The tests and technologies used by CHARM will improve cancer care and health outcomes for those living with NF1.

Initial CIHR grant received

March 6, 2018
August 2017

1st patient recruited at University Health Network

Our team of Clinical Research Coordinators recruited the first patients with hereditary cancer syndromes into the CHARM study during July of 2018, starting with Princess Margaret Cancer Centre and the rest of University Health Network.